Investigating the essential roles of Ubiquitin-like molecules and the Ubiquitin Proteasome System

Research Project 5.
In vivo requirements of the UBL modifier SUMO on SALL proteins function during steroidogenesis: D. melanogaster as a model system.

Objectives

Our aim is to study the in vivo requirements of the UBL modifier SUMO, by using the D. melanogaster steroid hormone production as a model system. We will focus on SALL proteins, zinc finger transcription factors involved in various human genetic syndromes and stem cells maintenance.

Partner

CIC bioGUNE

Group

Rosa Barrio

Fellow

Lucia Pirone