Investigating the essential roles of Ubiquitin-like molecules and the Ubiquitin Proteasome System
Research Project 5.
In vivo requirements of the UBL modifier SUMO on SALL proteins function during steroidogenesis: D. melanogaster as a model system.
Objectives
Our aim is to study the in vivo requirements of the UBL modifier SUMO, by using the D. melanogaster steroid hormone production as a model system. We will focus on SALL proteins, zinc finger transcription factors involved in various human genetic syndromes and stem cells maintenance.