Investigating the essential roles of Ubiquitin-like molecules and the Ubiquitin Proteasome System

Lucia Pirone

Education

  • January 2012 - December 2014
    UPStream PhD student at CIC bioGUNE. PhD advisor: Rosa Barrio
  • February 2011 - July 2011
    Leonardo Unipharma Project at CIC bioGUNE of Bilbao Functional Genomics Unit- Gene Silencing Platform Principal investigator: Rosa Barrio
  • October 2010 - January 2011
    Stage at EPA s.r.l. Ecologia Prevenzione Ambiente Pharmatrain project- Regione Lazio
  • November 2009
    State Qualification Exam for the Profession of Biologist in Italy
  • April 2009
    Laurea Specialistica (Master ) in Genetics and Molecular Biology, University of Rome “La Sapienza”, Rome, Italy. Graduated with thesis title “ Identification of 4-chlotothreonine biosynthetic cluster in Streptomyces sp. OH-5093”. Final mark: 110/110 cum laude.
  • February 2007
    Laurea (Bachelor) in Biological Sciences (bio-molecular track), University of Rome “La Sapienza”, Rome, Italy. Graduated with thesis title “CHL1 gene analysis in Saccharomyces cerevisiae”. Final mark : 103/110
Lucia Pirone

 

 

 

 

 

 

 

 

 

Publications

2013
Talamillo A, Herboso L, Pirone L, Pérez C, González M, Sánchez J, Mayor U, Lopitz-Otsoa F, Rodriguez M.S., Sutherland J.D. and Barrio R. Scavenger Receptors Mediate the Role of SUMO and Ftz-f1 in Drosophila Steroidogenesis. PLoS Genet 9(4): e1003473. doi:10.1371/journal.pgen.1003473 (2013).

2011
Sánchez J, Talamillo A, Gonzalez M, Sánchez-Pulido L, Jimenez S, Pirone L, Sutherland JD, Barrio R. Drosophila Sal and Salr are transcriptional repressors. Biochemical Journal, 438: 437-445.

2011
Monika González, Itziar Martín-Ruíz, Silvia Jiménez, Lucia Pirone, Rosa Barrio & James D. Sutherland. Generation of stable Drosophila cell lines using multicistronic vectors.  Scientifics Reports, 1:75.

Contributions to meetings

2014

L Pirone, C Pérez, U Mayor, JO Sigurðsson, JV Olsen, JD Sutherland, R Barrio. A comprehensive toolbox for the analysis of ubiquitin-like posttranslational modifications. Oral Presentation

EMBO Conference: Ubiquitin & ubiquitin-like proteins: At the crossroads from chromatin to protein. Buenos Aires, Argentina. 19-24/10/2014.

2013

E Ureña, C Pérez, MS Rodriguez, V Lang, L Pirone, JD Sutherland, R Barrio, D Martín. Evolution of SUMO protein functions in insects. Poster.

Insect Hormones (19th Ecdysone) International Workshop, Minneapolis, Minnesota, USA. 22-26/07/2013.

2012

 L. Pirone, C. Pérez, A. Talamillo, U. Mayor, S-Y. Lee, E. Ureña, D. Martín, R. Barrio and J. D. Sutherland. In vivo analysis of SUMOylated proteins from Drosophila melanogaster using improved strategies for expression, purification, and identification of conjugation site. 

FEBS Special Meeting in Protein Quality Control and Ubiquitin Systems in Health and Disease. 7th Inproteolys Meeting. Kusadasi, Turkey.13-17/11/2012.

2011
M. Rosaria Fullone, Rossella Miele, M. Carmela Bonaccorsi di Patti, Enrique Ros Herrera, Lucia Pirone, Lucia Cattaneo, Sara Marsango, Alessandro Paiardini and Ingeborg Grgurina. Molecular Cloning of the Biosynthetic Cluster Involved in the Production of 4-Chlorothreonine in Streptomyces sp. OH-5093: Insight into the Structure - Activity Relationship of a New Nonheme Fe(II) Halogenase.
NatPharma: Nature Aided Drug Discovery ( NADD). Napoli, Italy.

Partner

CIC bioGUNE

Group

Rosa Barrio