Investigating the essential roles of Ubiquitin-like molecules and the Ubiquitin Proteasome System

Katharina Witting

Education

  • 2006-2012
    Technical University of Berlin, Institute of Chemistry (Berlin, DE) Diploma in Chemistry
    Diploma Thesis: Elucidating the proteasomal regulation via the p38 MAPK pathway (NKI, Amsterdam)

Professional Experience

  • 2011-2012
    The Netherlands Cancer Institute (Amsterdam, NL)
    Diploma thesis:
    • Influence of p38 MAPK pathway on the proteasome activity
    • Establishing biochemical assays
  • 05.08.2011
    Technical University of Berlin, Institute of Organic Chemistry and Biochemistry (Berlin, DE)
    Intership:
    • Heterologous expression of vatious type III antibiotics.
  • 05-07.2010
    Technical University of Berlin, Institute of Organic Chemistry and Biochemistry (Berlin, DE)
    Intership:
    • Purification and in vitro assays of different LABKC mutants for elucidation of the Labyrinthopeptin-A2 Biosynthesis
  • 2008 – 2009
    Technical University of Berlin, Institute of Organic Chemistry and Biochemistry (Berlin, DE)
    Intership:
    • Fermentation, Purification and Generation of Abyssomycin C derivatives
    • Semisynthetic approaches for validation of possible biosynthetic routes of Abyssomycin C derivatives

Career Accomplishments

10.2012
Oncology Graduate School (OOA) Graduate Retreat (Amsterdam, NL)
Poster prize

2011
Scholarship (Berlin, DE)
Klaus Koch Stipendium der Klaus Koch Stiftung (TU Berlin)

Publications

2011

Witting, K.*, Suessmuth, R.D.
Discovery of Antibacterials and Other Bioactive Compounds from Microorgansims—Evaluating Methodologies for Discovery and Generation of Non-Ribosomal Peptide Antibiotics.
Curr. Drug Targets, 2011, 12(11), 1547-59

Confererences

Partner

NKI-AVL

Group

Huib Ovaa